90-day mortality of severe sepsis and septic shock is reduced by initiation of oral beta-blocker therapy and increased by discontinuation of a pre-existing beta-blocker treatment
نویسندگان
چکیده
Introduction A continuous infusion of the beta-blocker esmolol has recently been demonstrated to increase stroke volume without increasing norepinephrine dosage or impairing microcirculation in patients with septic shock [1]. In addition, a pre-existing oral therapy with beta-blockers was associated with a potential 28-day mortality survival benefit in septic patients [2]. The influence of a new initiated or discontinued oral beta-blocker therapy upon 90-day mortality, however, remains unclear.
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2015